Construction of poliovirus intertypic recombinants by use of cDNA.
نویسندگان
چکیده
We investigated the use of infectious cDNA for the production of poliovirus type 1-type 3 recombinants. One such recombinant virus was produced, but a second construct involving the transfer of part of the capsid protein region was not infectious. Our results suggest that the approach may prove valuable but that not all cDNA constructs will give rise to viable viruses.
منابع مشابه
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عنوان ژورنال:
- Journal of virology
دوره 57 3 شماره
صفحات -
تاریخ انتشار 1986